TPE filtration set

TPE Filtration Sets

TPE 1000 and TPE 2000 Pre-connected Sets for Therapeutic Plasma Exchange, powered by the PrisMax and Prismaflex systems.

Therapeutic plasma exchange is associated with positive clinical outcomes1

Therapeutic plasma exchange (TPE) is an extracorporeal blood purification technique used to treat patients with a variety of disorders; it has become a relatively common treatment modality. It is associated with positive clinical outcomes in the treatment of Guillain-Barré syndrome, thrombotic thrombocytopenic purpura (TTP), myasthenia gravis and Goodpasture syndrome.

Expand beyond CRRT to deliver membrane therapeutic plasma exchange in the ICU

Treatment indications for TPE have increased over time. TPE can be delivered in the ICU using Vantive’s PrisMax and Prismaflex systems, giving clinicians the flexibility to deliver multiple therapies at the bedside anytime, with ease and confidence, in a simple and efficient manner.

Hospitals that already own a PrisMax or Prismaflex device can run TPE without purchasing a new device.2

A clinician talks to a young patient who is lying in their hospital bed. There is a PrisMax machine in the background.

Filtration TPE sets powered by PrisMax and Prismaflex expand treatment options in the ICU

Simplicity and improved ease of use for TPE delivery

Setting up and delivering TPE therapy on the PrisMax and Prismaflex systems is similar to setting up a CRRT procedure.2 

The intuitive user interface of the PrisMax and Prismaflex systems may help to support therapy initiation.2,3

The systems offer the capability for citrate anticoagulation and an  integrated syringe pump for heparin anticoagulation.2

Enhanced safety features for greater confidence

The PrisMax and Prismaflex systems offer the ability to delay the start of therapy until the TPE circuit has been filled with blood before initiating treatment.2

The self-regulating pressure system can automatically accommodate blood flow rate adjustments.2

Flow-rate capabilities allow adjustments for lower-body-weight patients.2

Vantive offers different TPE filtration sets for plasma protein removal to meet individual patient needs

 

TPE 2000 set

TPE 1000 set

Patient Weight

Adult

>9 kg

Effective Surface Area

0.35 m2

0.15 m2

Blood Priming Volume

41 mL ± 10%

23 mL ± 10%

Blood Volume in Set

 

125 mL ± 10%

71 mL ± 10%

Minimum Blood Flow Rate

100 mL/min

50 mL/min

Maximum Blood Flow Rate

400 mL/min

180 mL/min

Plasmafilter Hollow Fiber

Polypropylene

Polypropylene

Related products

Important Safety Information

Please click here for important safety information.

Vantive, Prismaflex and PrisMax are trademarks of Vantive Health LLC or its affiliates.

References

  1. Padmanabhan A, Connelly‐Smith L, Aqui N, et al. Guidelines on the use of therapeutic apheresis in clinical practice–evidence‐based approach from the Writing Committee of the American Society for Apheresis: the eighth special issue. J Clin Apher. 2019;34:171-354.  

  2. Vantive Health LLC. PrisMax Operator’s Manual AW8061. 2024.

  3. Broman M, Bell M, Joannes-Boyau O, Ronco C. The novel PrisMax Continuous Renal Replacement Therapy system in a multinational,multicentre pilot setting. Blood Purif. 2018;46:220-227.