PrisMax System

The next-generation therapy system

The ever-changing challenges in the ICU can be demanding

At Vantive, we recognize the complex challenges providers face when caring for the most critically ill patients, after speaking with healthcare professionals around the world for 20+ years. Through this collaboration, we have identified three key challenges where Vantive can help:

1. Operational efficiency: high workload during therapy setup and delivery

2. Diverse treatment needs: patients requiring multi-organ support therapies

3. Complex clinical processes: complicated therapy setup and delivery

Compatible Products

CRRT Solutions

CRRT Filtersets

Filter Sets & Catheters

Introducing the PrisMax System: built to help providers overcome the challenges in the ICU

The PrisMax System helps address the key challenges in the ICU and takes extracorporeal therapies to the next level by offering improvements designed to:

Achieve operational simplicity
Help enable smart efficiencies
Enhance data-driven insights

Two female healthcare workers look at data on an tablet

Maximize simplicity

Offer seamless therapy delivery with end-to-end intuitive interface

Simplify the complexities of CRRT and other extracorporeal therapies with the user-friendly interface of the PrisMax System, which helps enable seamless therapy management, from setup to delivery.

Large 15-inch rotating, adjustable touchscreen for multidirectional viewing of critical data even from a distance
Simple step-by-step on-screen instructions with color coding and confirmation of completed steps with check marks
Continuous display of vital information to simplify monitoring
Troubleshooting information supported with images for guidance
Smart alarms designed to reduce device interactions and treatment interruptions

Enhance EMR connectivity with TrueVue Connect for auto-documentation

Help make documentation easier with TrueVue Connect, a digital add-on communication module, which helps enable auto-documentation with enhanced EMR connectivity.

Secure connection to the hospital’s EMR through wireless or wired connections
TrueVue Connect can also communicate using HL7 and is compatible with leading EMR systems and middleware vendors

Support alkalosis risk management with the normalized Net Buffer Load (nNBL)

The normalized Net Buffer Load (nNBL) is a parameter for alkalosis risk assessment during regional citrate anticoagulation (RCA). The nNBL is continuously displayed on the user interface of the PrisMax System during prescription setting and treatment.

Expand treatment possibilities

Deliver a range of therapies on the PrisMax System – CRRT, ECCO₂R, TPE and blood purification for sepsis management to remove cytokines and endotoxins – without adding complexities in delivery.

Deliver CRRT, ECCO₂R and blood purification for sepsis management as stand-alone therapies or in combination with a single vascular access.¹

A clinician uses the PrisMax system at the patient bedside

Blood purification for sepsis management (with or without AKI)

The PrisMax System is compatible with the Oxiris filterset, the only 3-in-1 blood purification filterset to effectively remove inflammatory mediators such as cytokines and endotoxins as a blood purification therapy for sepsis management. Therapy can be delivered as a stand alone hemoprofusion treatment or while delivering CRRT.^1,2

Integrate ECCO₂R therapy

The PrisMax System with the PrismaLung+ gas exchanger supports the delivery of ECCO2R either as a stand-alone therapy or in combination with CRRT and/or blood purification for sepsis management.¹

Healthcare professional interacts with the PrisMax system with a TPE filterset attached to it

Access TPE 24/7

With the PrisMax System, you can deliver round-the-clock TPE to support time-critical indications.¹

Smart efficiencies

Streamline clinical workflows and increase efficiency with the PrisMax System’s intelligent features that may help reduce device interactions and decrease therapy downtime.¹

Optimize your CRRT program with data-driven insights enabled by TrueVue Therapy Management.

Help optimize clinical workflows by reduced device interactions

The Auto-Effluent Drain accessory, which is available for the PrisMax System, helps in optimizing the workflow in your ICU by:

Potentially reducing bag changes by 60% and eliminating the need to change effluent bags manually, allowing more time for patient care³
Decreasing therapy downtime and potentially increasing therapy delivery time by up to 30 minutes per patient per day^3,4
You also have the choice to capture effluent in a bag or dispose of it directly into a drain depending on the clinical situation.

Focus more on patient care with intelligent automation

Smart alarms help prevent alarm fatigue by automatically clearing alarms that are displayed for only informative purposes, such as pressure alarms. They reduce device interactions during therapy delivery enabling nursing staff to focus more on patient care.¹

Advanced pressure management also minimizes alarms due to sudden pressure spikes caused by the patient moving.

Support CRRT improvements with data-driven insights

Take advantage of data-driven CRRT quality improvement programs with TrueVue Therapy Management that enables you to:

Use your hospital-specific data to support data-driven decision-making
Create standardized processes to help improve CRRT program efficiency

Learn more

Accuracy and system performance

Increase the accuracy of treatment delivery with the PrisMax System.

The Patient Fluid Removal (PFR) Catch-up helps clinicians meet prescribed fluid removal targets when treatment interruptions occur and helps deliver more accurate treatments compared to the Prismaflex system.¹

The TherMax blood warmer allows effective blood warming for extracorporeal therapies while giving physicians control of return blood temperature.¹

The PrisMax System’s technology includes the Patient Fluid Removal (PFR) Catch-Up, which uses intelligent pump adjustments to help meet prescribed fluid removal targets. This patented technology tracks therapy delivery and safely adjusts effluent pump speed to help meet clinically prescribed fluid removal targets — even when treatment interruptions occur for up to 10 minutes per instance.¹

In a clinical setting, the PrisMax System delivered 99.8% of prescribed patient fluid removal.³

The optional TherMax Blood Warmer brings an innovative approach to CRRT blood warming, allowing clinicians to set and achieve blood-warming targets.⁵

The TherMax Blood Warmer is controlled through the intuitive user interface of the PrisMax System and delivers effective blood warming for a range of therapies.

Independent from fluid flow rates and therapy interruptions, the TherMax Blood Warmer offers:

Efficient blood warming during CRRT
Reduced risk of hypothermia with precise control of return blood temperature between 35°C and 38°C
Easy warmer management through the PrisMax System user interface

Connect with us

Learn how we can help address challenges in the ICU.

Important Safety Information

Please click here for important safety information.

Vantive, GamCath, Oxiris, Prismaflex, Prismalung+, PrisMax, TherMax and TrueVue are trademarks of Vantive Health LLC or its affiliates.

References

Vantive Health LLC. PrisMax Operator’s Manual. The MDR Vantive Legal Manufacturer ROW. 2024. AW8200.
Vantive Health LLC. Oxiris Market Research 3-in-1. 2021. Internal Documentation.
Vantive Health LLC. PrisMax Limited Controlled Distribution Report. 2018. Internal Documentation.
Vantive Health LLC. Statistical Analysis, Summary of PrisMax LCD Data. 2018. Internal Documentation.
Vantive Health LLC. TherMax Operator’s Manual. 2025. AW7006.

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