Smiling man getting treatment

Special dialyzers


State-of-the art membrane designs supporting a variety of patient needs

Polyflux 2H and 6H dialyzers

Polyflux 2H/6H dialyzer series enables high flux dialysis compatibility and performance to low body weight patients, typically children1

 

Nephral ST dialyzer

Specialized for high biocompatibility and adsorption, Nephral ST dialyzer series feature a heparin adsorptive hydrogel for a reduced use of heparin during dialysis.2,3

Evodial dialyzer

Specialized for patients with a high risk of bleeding4,5

 

Theralite dialyzer

Created for multiple myeloma patients requiring hemodialysis treatments6,7


Advanced dialyzers that empower patients and healthcare providers alike

Each dialyzer features a unique membrane tailored to specific therapy and patient population needs and benefits from Vantive’s long history of expertise in performance, quality and simplicity. At Vantive we are committed to helping providers achieve the best possible outcomes for dialysis patients and provide the tools to do so.


Polyflux 2H and 6H dialyzers

Specialized for low body weight patients, Polyflux 2H and 6H dialyzers feature a unique Polyamix membrane that enables high-flux dialysis compatibility and performance for low body weight patients, typically children.1,8,9

 

Polyflux 2H and 6H dialyzers

Nephral ST dialyzer

Nephral ST dialyzer series features a heparin adsorptive hydrogel membrane for reduced use of heparin during dialysis.10 while also reducing the systemic use of heparin. It may be an alternative for patients with hypersensitivity to conventional membranes.11

 

specialDialyzer

Evodial dialyzer

Specialized for patients with a high risk of bleeding,4,5 Evodial dialyzer series has been designed with a HeprAN heparin-grafted membrane2,10 and provides a convenient solution for patients requiring reduced or even heparin-free dialysis. 

Do not use Evodial in patients with a known allergy to heparin or type II thrombocytopenia caused by heparin (HIT syndrome type II).

Evodial Dialyzers

Theralite dialyzer

Created for multiple myeloma patients requiring hemodialysis treatment, Theralite dialyzer proprietary high cut-off (HCO) membrane targets the removal of the free light chains (FLC) proteins that can be overproduced and lead to Acute Kidney Injury.6,7 

 

Do not use Theralite dialyzer for HDF (hemodiafiltration) or HF (hemofiltration) due to higher permeability of larger molecular weight proteins such as albumin.

Theralite dialyzer must not be used for pediatric dialysis and for regular treatment of chronic renal failure.

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The images are for illustration purposes only and may differ from the actual product

 

Vantive, Evodial, Nephral, Polyamix, Polyflux and Theralite are trademarks of Vantive Health LLC or its affiliates.

 

References
  1. Goldstein SL, Allsteadt A, Beck W, Nilsson L-G.  Evaluation of the Polyflux® 6H Dialyzer in pediatric patients receiving maintenance hemodialysis. Int J Artif Organs. 2007;30:321-324.

  2. Chanard J, Lavaud S, Maheut H, et al. The clinical evaluation of low-dose heparin in haemodialysis: a prospective study using the heparin-coated AN69 ST membrane. Nephrol Dial Transplant. 2008;23:2003-2009.

  3. Lavaud S, et al. Assessment of the heparin-binding AN69 ST hemodialysis membrane: II. Clinical studies without heparin administration. ASAIO J. 2005; 51:348-51.

  4. Laville M, Dorval M, Fort Ros J, et al. Results of the HepZero study comparing heparin-grafted membrane and standard care show that heparin-grafted dialyzer is safe and easy to use for heparin-free dialysis.. Kidney Int. 2014; 86:1260-1267.

  5. Kessler M, Moureau F, Nguyen P, et al. Anticoagulation in chronic hemodialysis: progress toward an optimal approach. Semin Dial. 2015; 28:474-489.

  6. Boschetti-de-Fierro A, Voigt M, Storr M, Krause B. Extended characterization of a new class of membranes for blood purification: the high cut-off membranes. Int J Artif Organs. 2013;36:455-463.

  7. Hutchison CA, Batuman V, Behrens J, et al. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 2012;8:43-51.

  8. Ronco C, Crepaldi C, Brendolan A, et al. Evolution of synthetic membranes for blood purification: the case of the Polyflux family. Nephrol Dial Transplant. 2003;18(7):vii10-20.

  9. Warady BA, et al. Maintenance hemodialysis during infancy. Pediatric Dialysis. Chapter 19. 2012. Edited by Ulinski T, Cochat P.

  10. Thomas M, Moriyama K, Ledebo I. AN69: Evolution of the world's first high permeability membrane. Contrib Nephrol. 2011;173:119-129.

  11. Bouman CS, van Olden RW, Stoutenbeek CP. Cytokine filtration and adsorption during pre- and postdilution hemofiltration in four different membranes. Blood Purif. 1998;16:261-268.