Patient receiving treatment

Polyflux H and Polyflux L dialyzer series

Polyflux dialyzers are offered in a high-flux series — Polyflux H dialyzer — and a low-flux series — Polyflux L dialyzer. 

Polyflux H dialyzer: for effective convective therapies and regular high-flux HD

Polyflux H dialyzer series is a range of dialyzers that effectively support the delivery of high-volume convective therapies1 (HDF or HF mode), as well as regular high-flux hemodialysis. Polyflux H dialyzer series is proven to deliver biocompatibility2 and endotoxin retention3 with consistent performance. The series helps control the loss of essential proteins such as albumin,4 which is particularly challenging at high flows and transmembrane pressures.

Polyflux H dialyzers are aimed at delivering stable and high-performing convective treatments, supporting a consistent reach of high volumes of substitution fluid.

Polyflux H Dialyzers

Benefits of Polyflux H dialyzer series

#1

Promoting biocompatibility2,3 with convective volumes in mind

#2

3-layer Polyamix membrane has been designed to optimize the combination of high diffusive and convective transport rates

#3

Narrow pore size distribution is responsible for a carefully controlled albumin selectivity, combined with an effective permeability to small and conventional middle molecules3

#4

Polyflux H dialyzers are steam sterilized inside-out* and designed to promote biocompatibility, avoiding the risks associated with the exposure to chemicals such as ethylene oxide and manufacturing residues5,6

Polyflux L dialyzer: a proven balance of quality and performance in low-flux

Polyflux L dialyzer series is a range of dialyzers specialized for low-flux hemodialysis treatments, featuring a distinctive membrane that acts as an effective barrier to potential fluid contaminants, while still delivering high performance.7 Polyflux L series is proven to deliver biocompatible yet effective low-flux therapies

Polyflux L dialyzers

Benefits of Polyflux L dialyzer series

#1

Promoting biocompatibility3,5 with high performance in mind

#2

Distinctive membrane design that prevents endotoxins from crossing the dialyzer membrane2,3

#3

Steam sterilized inside-out, preventing exposure to chemicals such as ethylene oxide and manufacturing residues5,6

#4

Exclusive 3-layered membrane structure, designed to support a stable high performance over time7

Related products

Important Safety Information

Please click here for important safety information.

The images are for illustration purposes only and may differ from the actual product.

 

Vantive, Artis Physio, Polyamix, Polyflux and Revaclear are trademarks of Vantive Health LLC or its affiliates.

References

  1. Maduell F, Moreso F, Pons M, et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients [published correction appears in J Am Soc Nephrol. 2014 May;25(5):1130]. J Am Soc Nephrol. 2013;24(3):487-497. 

  2. Schepers E, Glorieux G, Eloot S, et al. Assessment of the association between increasing membrane pore size and endotoxin permeability using a novel experimental dialysis simulation set-up. BMC Nephrol. 2018;19(1):1.

  3. Ronco C, Crepaldi C, Brendolan A, et al. Evolution of synthetic membranes for blood purification: the case of the Polyflux family. Nephrol Dial Transplant. 2003;18 Suppl 7:vii10-vii55.

  4. Potier J, Queffeulou G, Bouet J. Are all dialyzers compatible with the convective volumes suggested for postdilution online hemodiafiltration?. Int J Artif Organs. 2016;39(9):460-470.

  5. Golli-Bennour EE, Kouidhi B, Dey M, et al. Cytotoxic effects exerted by polyarylsulfone dialyser membranes depend on different sterilization processes. Int Urol Nephrol. 2011;43(2):483-490. 

  6. Purello D'Ambrosio F, Savica V, Gangemi S, et al. Ethylene oxide allergy in dialysis patients. Nephrol Dial Transplant. 1997;12(7):1461-1463. 

  7. Vantive Health LLC. Polyflux L Instructions for Use. 2009; N50 403; version 010. Data on file.